In the Spider-Boy: Team Up comic, Spider-Boy saves the life of a boy named Mig-El Gand (an amalgamation of M'Onel (Lar Gand) and Spider-Man 2099 (Miguel O'Hara)) who had been poisoned by a radiation beam. Spider-Boy sends Mig-El into an alternate dimension, where he waits 100 years in suspended animation. In the year 2099, he is returned to his home reality and given a serum of spider-DNA (developed by Spider-Boy in the future). The serum gives Mig-El spider-like powers of superhuman strength, speed, agility, wall-crawling, and the ability to fire webs from his fingertips. Mig-El becomes Spider-Boy 2099, and when Spider-Boy is attacked by an extadimensional villain, Spider-Boy 2099 time-travels to the past to save his predecessor. After the two arachnid heroes defeat the villain, Spider-Boy 2099 returns to his new home of 2099, and tells Spider-Boy that his life will never be the same after he marries Insect Queen. Spider-Boy 2099 is a member of the Legion Of Galactic Guardians 2099 (an amalgamation of the Legion of Super-Heroes and the Guardians of the Galaxy).